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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often described as focusing on practical aspects of design that include the recruitment and consent process, as well as adherence and the use of routinely available equipment.
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A pragmatic trial that uses different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, which is vital for pragmatic trials to be valid and to reduce bias in the results, is also necessary. However, too much heterogeneity can cause problems with the design of the trial.
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The aim of pragmatic trials is to mimic real-life situations and achieve maximum validity externally. They are typically commissioned by practitioners and policy makers to aid in their decision-making. They can also be used to determine the causality of an intervention with its outcomes. However, they should not be used in lieu for the use of explanation studies.
The pragmatism concept is controversial and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which validate a physiological or clinical hypothesis, and pragmatic trials that inform policy and
프라그마틱 슬롯 조작 공식홈페이지 -
Http://Istartw.Lineageinc.Com/ - practice decisions. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a practical study, including recruitment, design,
프라그마틱 슬롯 체험 implementation of the intervention, and follow-up.
There is a growing trend in the number of pragmatic trials published. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to remember, however, that the majority of studies were conducted in primary-care settings.