ADHD Medication During Pregnancy and Breastfeeding
Women with ADHD must make a difficult decision on whether to keep or stop taking ADHD medication during pregnancy and breastfeeding. There are few data on how exposure to ADHD for a long time could affect the fetus.
A recent study published in Molecular Psychiatry shows that children exposed to ADHD medication in utero do not develop neurological developmental disorders such as hearing or vision impairment seizures, febrile seizures or IQ impairment. The authors acknowledge that more high-quality studies are needed.
Risk/Benefit Analysis
Women who are pregnant and taking ADHD medications must weigh the benefits of taking them against potential risks to the fetus. The doctors don't have the information to provide clear recommendations but they can provide information about risks and benefits to assist pregnant women to make an informed decision.
A study published in Molecular Psychiatry found that women who were taking ADHD medications during their early pregnancy did not face a significantly increased risk of fetal heart malformations or major structural birth defects. Researchers used a large population-based study of case control to examine the prevalence of structural defects that were major in infants who were born to mothers who used stimulants during pregnancy. Pediatric cardiologists and clinical geneticists looked over the cases to ensure an accurate classification of the cases and to reduce the chance of bias.
The study conducted by the researchers was not without its limitations. Researchers were unable to, in the first place to distinguish the effects of the medication from the disorder. This limitation makes it difficult to know whether the small differences observed in the exposed groups are due to medication use or the confounding effect of comorbidities. The researchers also did not study long-term outcomes for the offspring.
The study revealed that infants whose mothers took ADHD medication during pregnancy were at a slightly higher chance of being admitted to the neonatal care unit (NICU) as compared to those whose mothers did not use any medication during pregnancy or had quit taking the
medication given for adhd prior to or during pregnancy. This was due to central nervous system disorders, and the increased risk of admission was not found to be influenced by which stimulant medications were taken during pregnancy.
Women who took stimulant ADHD medication during pregnancy were also at an increased chance of having a caesarean delivery or having a baby with low Apgar score (less than 7). These increases did appear to be independent
types of adhd medication uk the type of medication used during pregnancy.
The researchers suggest that the small risk associated with the use of ADHD medications during early pregnancy could be offset by the greater benefit for both mother and child of continuing treatment for the woman's condition. Doctors should discuss with their patients about this and, if possible, help them develop coping skills that could reduce the effects of her disorder on her daily life and relationships.
Medication Interactions
As more women than ever are being diagnosed with ADHD and treated with medication, the dilemma of whether to keep or discontinue treatment during pregnancy is a question that more and more doctors confront. These decisions are often made without clear and authoritative evidence. Instead, doctors must weigh their own knowledge and experience, as well as the experiences of other doctors, and the research on the subject.
The issue of risk for infants can be difficult to determine. The research that has been conducted on this topic is based on observation rather than controlled studies and many of the findings are in conflict. Most studies focus on live-births, which could underestimate the severity of teratogenic effects which can cause abortions or terminations of pregnancy. The study discussed in the journal club addresses these limitations by analyzing information on deceased and live births.
The conclusion: While some studies have shown that there is a positive correlation between ADHD medications and the possibility of certain birth defects, other studies have found no connection and the majority of studies demonstrate a neutral or slight negative effect. As a result an accurate risk-benefit analysis is required in every instance.
For a lot of women with ADHD who suffer from ADHD, the decision to discontinue medication is difficult, if not impossible. In a recent article in the Archives of Women's Mental Health, psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can cause depression, feelings of loneliness, and family conflict for patients with ADHD. The loss of medication can also affect the ability to drive safely and to perform work-related tasks which are essential aspects of everyday life for people with ADHD.
She suggests that women who are unsure whether to continue taking the medication or stop it due to their pregnancy educate family members, colleagues, and their friends about the condition, the impact on daily functioning and the benefits of continuing the current treatment. It can also help women feel confident about her decision. It is important to remember that certain medications are able to pass through the placenta, so if the patient decides to stop her ADHD medication during pregnancy and breastfeeding, she should be aware that traces of the medication could be passed on to the baby.
Risk of Birth Defects
As the use and misuse of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) is increasing as does the concern about the possible effects of the drugs on the fetuses. A recent study published in the journal Molecular Psychiatry adds to the existing information on this topic. Researchers used two huge data sets to examine more than 4.3 million pregnancy and determine if the use of stimulant medications increased the risk of birth defects. Researchers found that while the overall risk is low, the first trimester ADHD medication use was associated with slightly higher risk of certain heart defects, like ventriculoseptal defects.
The authors of the study didn't find any association between the use of early medications and congenital anomalies such as facial deformities or club feet. The results are consistent with previous studies showing an increase, but not significant, in the risk of developing cardiac malformations among women who began taking ADHD medications before the birth of their child. The risk grew during the latter part of pregnancy, when a lot of women decide to stop taking their ADHD medication.
Women
who can prescribe adhd medication for adults were taking ADHD medication in the first trimester were more likely need a caesarean and also have an insufficient Apgar after delivery, and have a baby who needed breathing assistance after birth. However the authors of the study were unable to eliminate selection bias by limiting the study to women who did not have any other medical conditions that could be a contributing factor to these findings.
Researchers hope that their research will provide doctors with information when they encounter pregnant women. They suggest that although a discussion of the benefits and risks is important but the decision to stop or continue treatment should be based on each woman's needs and the severity of her ADHD symptoms.
The authors also advise that while discontinuing the medications is an option, it isn't an option that is recommended due to the high prevalence of depression and other mental health problems among women who are pregnant or who are recently postpartum. Additionally, research suggests that women who stop taking their medications will have a difficult transitioning to life without them after the baby is born.
Nursing
It can be overwhelming becoming a mother. Women with ADHD who must work through their symptoms while attending physician appointments as well as preparing for the arrival of a child and getting used to new routines at home may face a lot of challenges. Many women opt to continue taking their
ADHD medication during pregnancy.
The risk to a breastfeeding infant is minimal because the majority of stimulant medications passes through breast milk at low levels. However, the rate of medication exposure to the infant can differ based on the dosage, frequency it is administered and the time of day it is administered. In addition, various drugs enter the infant's system through the gastrointestinal tract or breast milk. The effect on the health of a newborn is not fully understood.
Some physicians may discontinue stimulant medication during a woman's pregnancy due to the absence of research. This is a complicated decision for the patient, who must weigh the benefits of continuing her medication with the potential risks to the fetus. As long as more information is available, GPs may ask pregnant patients whether they have a background of ADHD or if they intend to take medication in the perinatal stage.
A growing number of studies have shown that women can continue to take their ADHD medication during pregnancy and while breastfeeding. In response, an increasing number of patients are opting to do so. They have concluded after consulting with their physicians, that the benefits of continuing their current medication outweigh any potential risks.
Women with ADHD who are planning to breastfeed should seek the advice of a specialist psychiatrist prior to becoming pregnant. They should discuss their medication with their prescriber as well as the pros and cons of continuing treatment. This includes non-pharmacological strategies. Psychoeducation should also be offered to help women with ADHD recognize their symptoms and the root cause Learn about the available treatment options and reinforce existing strategies for coping. This should include an approach that is multidisciplinary, including the GP as well as obstetricians, psychiatry and obstetricians. Counselling for pregnancy should include the discussion of a treatment plan for both mother and child, as well as monitoring for signs of deterioration and the need for adjustments to the medication regimen.